Research
My research focuses on the application of brain stimulation techniques especially Transcranial Magnetic Stimulation (TMS) in basic science e.g., in combination with electrophysiological measures as well as a treatment option for neuro-psychiatric diseases such as tinnitus. Over the course of my academic career I contributed to 37 scientific publications in the field of brain stimulation and/ tinnitus and gave several science talks at international conferences.
Selected Publications
Schoisswohl, S., Basso, L., Simoes, J., Engelke, M., Langguth, B., Mazurek, B., Lopez-Escamez, J. A., Kikidis, D., Cima, R., Bernal-Robledano, A., Boecking, B., Bulla, J., Cederroth, C. R., Denys, S., Escalera-Balsera, A., Gallego-Martinez, A., Gallus, S., Hidalgo-Lopez, L., Jarach, C. M., … Schlee, W. (2024). Single versus Combination Treatment in Tinnitus: An International, Multicentre, Parallel-arm, Superiority, Randomised Controlled Trial (p. 2024.01.09.24300978). medRxiv. https://doi.org/10.1101/2024.01.09.24300978
Schoisswohl, S., Kanig, C., Osnabruegge, M., Agboada, D., Langguth, B., Rethwilm, R., Hebel, T., Abdelnaim, M. A., Mack, W., Seiberl, W., Kuder, M., & Schecklmann, M. (2024). Monitoring changes in TMS-evoked EEG and EMG activity during 1 Hz rTMS of the healthy motor cortex. eNeuro, ENEURO.0309-23.2024. https://doi.org/10.1523/ENEURO.0309-23.2024
Schoisswohl, S., Langguth, B., Weber, F. C., Abdelnaim, M. A., Hebel, T., Mack, W., & Schecklmann, M. (2023). One way or another: Treatment effects of 1 Hz rTMS using different current directions in a small sample of tinnitus patients. Neuroscience Letters, 797, 137026. https://doi.org/10.1016/j.neulet.2022.137026
Prei, K., Kanig, C., Osnabrügge, M., Langguth, B., Mack, W., Abdelnaim, M., Schecklmann, M., & Schoisswohl, S. (2023). Limited evidence for reliability of low and high frequency rTMS over the motor cortex. Brain Research, 148534. https://doi.org/10.1016/j.brainres.2023.148534
Osnabruegge, M., Kanig, C., Schwitzgebel, F., Litschel, K., Seiberl, W., Mack, W., Schecklmann, M., & Schoisswohl, S. (2023). On the reliability of motor evoked potentials in hand muscles of healthy adults: A systematic review. Frontiers in Human Neuroscience, 17. https://www.frontiersin.org/articles/10.3389/fnhum.2023.1237712
Schoisswohl, S., Langguth, B., Hebel, T., Vielsmeier, V., Abdelnaim, M. A., & Schecklmann, M. (2022). Personalization of Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Subjective Tinnitus. Brain Sciences, 12(2), Article 2. https://doi.org/10.3390/brainsci12020203
Schoisswohl, S., Schecklmann, M., Langguth, B., Schlee, W., & Neff, P. (2021). Neurophysiological correlates of residual inhibition in tinnitus: Hints for trait-like EEG power spectra. Clinical Neurophysiology, 132(7), 1694–1707. https://doi.org/10.1016/j.clinph.2021.03.038
Full Publication List (H-Index 10)
2024
Schoisswohl, S., Kanig, C., Osnabruegge, M., Agboada, D., Langguth, B., Rethwilm, R., Hebel, T., Abdelnaim, M. A., Mack, W., Seiberl, W., Kuder, M., & Schecklmann, M. (2024). Monitoring changes in TMS-evoked EEG and EMG activity during 1 Hz rTMS of the healthy motor cortex. eNeuro, ENEURO.0309-23.2024. https://doi.org/10.1523/ENEURO.0309-23.2024
Osnabruegge, M., Kanig, C., Schoisswohl, S., Litschel, K., Mack, W., Schecklmann, M., Langguth, B., & Schwitzgebel, F. (2024). Variability of pulse width in transcranial magnetic stimulation. Journal of Neural Engineering, 21(2), 026035. https://doi.org/10.1088/1741-2552/ad367a
Schoisswohl, S., Basso, L., Simoes, J., Engelke, M., Langguth, B., Mazurek, B., Lopez-Escamez, J. A., Kikidis, D., Cima, R., Bernal-Robledano, A., Boecking, B., Bulla, J., Cederroth, C. R., Denys, S., Escalera-Balsera, A., Gallego-Martinez, A., Gallus, S., Hidalgo-Lopez, L., Jarach, C. M., … Schlee, W. (2024). Single versus Combination Treatment in Tinnitus: An International, Multicentre, Parallel-arm, Superiority, Randomised Controlled Trial (p. 2024.01.09.24300978). medRxiv. https://doi.org/10.1101/2024.01.09.24300978
Hebel, T., Schecklmann, M., Abdelnaim, M. A., Weber, F. C., Langguth, B., & Schoisswohl, S. (2024). Left prefrontal intermittent theta burst stimulation ameliorates tinnitus distress and symptoms of depression – A feasibility study. Neuroscience Letters, 137726. https://doi.org/10.1016/j.neulet.2024.137726
2023
Schoisswohl, S., Langguth, B., Weber, F. C., Abdelnaim, M. A., Hebel, T., & Schecklmann, M. (2023). Activate & fire: A feasibility study in combining acoustic stimulation and continuous theta burst stimulation in chronic tinnitus. BMC Neurology, 23(1), 14. https://doi.org/10.1186/s12883-022-03036-y
Schoisswohl, S., Langguth, B., Weber, F. C., Abdelnaim, M. A., Hebel, T., Mack, W., & Schecklmann, M. (2023). One way or another: Treatment effects of 1 Hz rTMS using different current directions in a small sample of tinnitus patients. Neuroscience Letters, 797, 137026. https://doi.org/10.1016/j.neulet.2022.137026
Agboada, D., Osnabruegge, M., Rethwilm, R., Kanig, C., Schwitzgebel, F., Mack, W., Schecklmann, M., Seiberl, W. & Schoisswohl, S. (accepted). Semi-automated hotspot search (SAMHS): A framework towards an optimised approach for hotspot identification. Frontiers in Human Neuroscience - Brain Imaging and Stimulation.
Bernal-Robledano, A., Perez-Carpena, P., Kikidis, D., Mazurek, B., Schoisswohl, S., Staudinger, S., Langguth, B., Schlee, W., & Lopez-Escamez, J. A. (2023). Cognitive screening and hearing assessment in patients with chronic tinnitus. Clinical and Experimental Otorhinolaryngology. https://e-ceo.org/journal/view.php?doi=10.21053/ceo.2023.00808
Prei, K., Kanig, C., Osnabrügge, M., Langguth, B., Mack, W., Abdelnaim, M., Schecklmann, M., & Schoisswohl, S. (2023). Limited evidence for reliability of low and high frequency rTMS over the motor cortex. Brain Research, 148534. https://doi.org/10.1016/j.brainres.2023.148534
Osnabruegge, M., Kanig, C., Schwitzgebel, F., Litschel, K., Seiberl, W., Mack, W., Schecklmann, M., & Schoisswohl, S. (2023). On the reliability of motor evoked potentials in hand muscles of healthy adults: A systematic review. Frontiers in Human Neuroscience, 17. https://www.frontiersin.org/articles/10.3389/fnhum.2023.1237712
Kanig, C., Osnabruegge, M., Schwitzgebel, F., Litschel, K., Seiberl, W., Mack, W., Schoisswohl,
S. & Schecklmann, M. (2023). Retest-Reliability of Repetitive Transcranial Magnetic Stimulation over the Healthy Human Motor Cortex: A Systematic Review and Meta-Analysis. Frontiers in Human Neuroscience, 17. https://www.frontiersin.org/articles/10.3389/fnhum.2023.1237713
Abdelnaim, M. A., Lang-Hambauer, V., Hebel, T., Schoisswohl, S., Schecklmann, M., Deuter,
D., Schlaier, J. & Langguth, B. (2023). Deep Brain Stimulation for treatment resistant Obsessive Compulsive Disorder: an observational study with ten patients under real-life conditions. Frontiers in Psychiatry, 14. https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1242566
Schecklmann, M., Weber, F. C., Lehner, A., Langguth, B., & Schoisswohl, S. (2023). Cognitive Behavioral Group Therapy for Chronic Tinnitus in a German Tertiary Clinical Real-World Setting. International Journal of Environmental Research and Public Health, 20(6), Article 6. https://doi.org/10.3390/ijerph20064982
Engelke, M., Simões, J., Vogel, C., Schoisswohl, S., Schecklmann, M., Wölflick, S., Pryss, R., Probst, T., Langguth, B., & Schlee, W. (2023). Pilot study of a smartphone-based tinnitus therapy using structured counseling and sound therapy: A multiple-baseline design with ecological momentary assessment. PLOS Digital Health, 2(1), e0000183. https://doi.org/10.1371/journal.pdig.0000183
Simoes, J. P., Schoisswohl, S., Schlee, W., Basso, L., Bernal-Robledano, A., Boecking, B., Cima, R., Denys, S., Engelke, M., Escalera-Balsera, A., Gallego-Martinez, A., Gallus, S., Kikidis, D., López-Escámez, J. A., Marcrum, S. C., Markatos, N., Martin-Lagos, J., Martinez-Martinez, M., Mazurek, B., … Langguth, B. (2023). The statistical analysis plan for the unification of treatments and interventions for tinnitus patients randomized clinical trial (UNITI-RCT). Trials, 24(1), 472. https://doi.org/10.1186/s13063-023-07303-2
2022
Schoisswohl, S., Langguth, B., Hebel, T., Vielsmeier, V., Abdelnaim, M. A., & Schecklmann, M. (2022). Personalization of Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Subjective Tinnitus. Brain Sciences, 12(2), Article 2. https://doi.org/10.3390/brainsci12020203
Hebel, T., Langguth, B., Schecklmann, M., Schoisswohl, S., Staudinger, S., Schiller, A., Ustohal, L., Sverak, T., Horky, M., Kasparek, T., Skront, T., Hyza, M., Poeppl, T. B., Riester, M. L., Schwemmer, L., Zimmermann, S., & Sakreida, K. (2022). Rationale and study design of a trial to assess rTMS add-on value for the amelioration of negative symptoms of schizophrenia (RADOVAN). Contemporary Clinical Trials Communications, 100891. https://doi.org/10.1016/j.conctc.2022.100891
Schlee, W., Neff, P., Simoes, J., Langguth, B., Schoisswohl, S., Steinberger, H., Norman, M., Spiliopoulou, M., Schobel, J., Hannemann, R., & Pryss, R. (2022). Smartphone-Guided Educational Counseling and Self-Help for Chronic Tinnitus. Journal of Clinical Medicine, 11(7), Article 7. https://doi.org/10.3390/jcm11071825
Shekhawat, G. S., Schonell, S., Schoisswohl, S., Biswas, R., Schiller, A., & Schlee, W. (2022). European School for Interdisciplinary Tinnitus (ESIT): A global research training initiative. International Journal for Students as Partners, 6(1), 11. https://doi.org/10.15173/ijsap.v6i1.4877
Weber, F. C., Schlee, W., Langguth, B., Schecklmann, M., Schoisswohl, S., Wetter, T. C., & Simões, J. (2022). Low Sleep Satisfaction Is Related to High Disease Burden in Tinnitus. International Journal of Environmental Research and Public Health, 19(17), Article 17. https://doi.org/10.3390/ijerph191711005
2021
Schoisswohl, S., Langguth, B., Gebel, N., Poeppl, T. B., Kreuzer, P. M., & Schecklmann, M. (2021). Electrophysiological evaluation of high and low-frequency transcranial random noise stimulation over the auditory cortex. In Progress in Brain Research (Vol. 263, pp. 95–108). Elsevier. https://doi.org/10.1016/bs.pbr.2020.08.009
Schoisswohl, S., Langguth, B., Hebel, T., Abdelnaim, M. A., Volberg, G., & Schecklmann, M. (2021). Heading for Personalized rTMS in Tinnitus: Reliability of Individualized Stimulation Protocols in Behavioral and Electrophysiological Responses. Journal of Personalized Medicine, 11(6), Article 6. https://doi.org/10.3390/jpm11060536
Schoisswohl, S., Langguth, B., Schecklmann, M., Bernal-Robledano, A., Boecking, B., Cederroth, C. R., Chalanouli, D., Cima, R., Denys, S., Dettling-Papargyris, J., Escalera-Balsera, A., Espinosa-Sanchez, J. M., Gallego-Martinez, A., Giannopoulou, E., Hidalgo-Lopez, L., Hummel, M., Kikidis, D., Koller, M., Lopez-Escamez, J. A., … Schlee, W. (2021). Unification of Treatments and Interventions for Tinnitus Patients (UNITI): A study protocol for a multi-center randomized clinical trial. Trials, 22(1), 875. https://doi.org/10.1186/s13063-021-05835-z
Schoisswohl, S., Schecklmann, M., Langguth, B., Schlee, W., & Neff, P. (2021). Neurophysiological correlates of residual inhibition in tinnitus: Hints for trait-like EEG power spectra. Clinical Neurophysiology, 132(7), 1694–1707. https://doi.org/10.1016/j.clinph.2021.03.038
Neff, P. K. A., Schoisswohl, S., Simoes, J., Staudinger, S., Langguth, B., Schecklmann, M., & Schlee, W. (2021). Prolonged tinnitus suppression after short-term acoustic stimulation. In Progress in Brain Research. Elsevier. https://doi.org/10.1016/bs.pbr.2021.02.004
Hafner, A., Schoisswohl, S., Simoes, J., Schlee, W., Schecklmann, M., Langguth, B., & Neff, P. (2021). Impact of personality on acoustic tinnitus suppression and emotional reaction to stimuli sounds. In Progress in Brain Research (Vol. 260, pp. 187–203). Elsevier. https://doi.org/10.1016/bs.pbr.2020.08.004
Schlee, W., Schoisswohl, S., Staudinger, S., Schiller, A., Lehner, A., Langguth, B., Schecklmann, M., Simoes, J., Neff, P., Marcrum, S. C., Spiliopoulou, M., Niemann, U., Schleicher, M., Unnikrishnan, V., Puga, C., Mulansky, L., Pryss, R., Vogel, C., Allgaier, J., … Kikidis, D. (2021). Towards a unification of treatments and interventions for tinnitus patients: The EU research and innovation action UNITI. Progress in Brain Research, 260, 441–451. https://doi.org/10.1016/bs.pbr.2020.12.005
Biswas, R., Schiller, A., Casolani, C., Daoud, E., Dode, A., Genitsaridi, E., Jacquemin, L., Liyanage, N., Lourenco, M., Makani, P., Parameshwarappa, V., Riha, C., Santacruz, J. L., Shabbir, M., Simoes, J., Trpchevska, N., & Schoisswohl, S. (2021). Doctoral Studies as part of an Innovative Training Network (ITN): Early Stage Researcher (ESR) experiences Open Res Europe 2021, 1:34. https://doi.org/10.12688/openreseurope.13094.2
Allgaier, J., Neff, P., Schlee, W., Schoisswohl, S., & Pryss, R. (2021). Deep Learning End-to-End Approach for the Prediction of Tinnitus based on EEG Data*. 2021 43rd Annual International Conference of the IEEE Engineering in Medicine Biology Society (EMBC), 816–819. https://doi.org/10.1109/EMBC46164.2021.9629964
Hebel, T., Göllnitz, A., Schoisswohl, S., Weber, F. C., Abdelnaim, M., Wetter, T. C., Rupprecht, R., Langguth, B., & Schecklmann, M. (2021). A direct comparison of neuronavigated and non-neuronavigated intermittent theta burst stimulation in the treatment of depression. Brain Stimulation, 14(2), 335–343. https://doi.org/10.1016/j.brs.2021.01.013
Simoes, J. P., Daoud, E., Shabbir, M., Amanat, S., Assouly, K., Biswas, R., Casolani, C., Dode, A., Enzler, F., Jacquemin, L., Joergensen, M., Kok, T., Liyange, N., Lourenco, M., Makani, P., Mehdi, M., Ramadhani, A., Riha, C., Santacruz, J. L., … Genitsaridi, E. (2021). Multidisciplinary Tinnitus Research: Challenges and Future Directions from the Perspective of Early Stage Researchers. Frontiers in Aging Neuroscience, 13. https://doi.org/10.3389/fnagi.2021.647285
2020
Schoisswohl, S., Langguth, B., & Schecklmann, M. (2020). Short-Term Tinnitus Suppression With Electric-Field Guided rTMS for Individualizing rTMS Treatment: A Technical Feasibility Report. Frontiers in Neurology, 11, 86. https://doi.org/10.3389/fneur.2020.00086
Schlee, W., Hølleland, S., Bulla, J., Simoes, J., Neff, P., Schoisswohl, S., Woelflick, S., Schecklmann, M., Schiller, A., Staudinger, S., Probst, T., & Langguth, B. (2020). The Effect of Environmental Stressors on Tinnitus: A Prospective Longitudinal Study on the Impact of the COVID-19 Pandemic. Journal of Clinical Medicine, 9(9), Article 9. https://doi.org/10.3390/jcm9092756
2019
Schoisswohl, S., Agrawal, K., Simoes, J., Neff, P., Schlee, W., Langguth, B., & Schecklmann, M. (2019). RTMS parameters in tinnitus trials: A systematic review. Scientific Reports, 9(1), 1–11. https://doi.org/10.1038/s41598-019-48750-9
Schoisswohl, S., Arnds, J., Schecklmann, M., Langguth, B., Schlee, W., & Neff, P. (2019). Amplitude Modulated Noise for Tinnitus Suppression in Tonal and Noise-Like Tinnitus. Audiology and Neurotology, 24(6), 309–321. https://doi.org/10.1159/000504593
Genitsaridi, E., Partyka, M., Gallus, S., Lopez-Escamez, J. A., Schecklmann, M., Mielczarek, M., Trpchevska, N., Santacruz, J. L., Schoisswohl, S., Riha, C., Lourenco, M., Biswas, R., Liyanage, N., Cederroth, C. R., Perez-Carpena, P., Devos, J., Fuller, T., Edvall, N. K., Hellberg, M. P., … Hall, D. A. (2019). Standardised profiling for tinnitus research: The European School for Interdisciplinary Tinnitus Research Screening Questionnaire (ESIT-SQ). Hearing Research, 377, 353–359. https://doi.org/10.1016/j.heares.2019.02.017
Simoes, J., Neff, P., Schoisswohl, S., Bulla, J., Schecklmann, M., Harrison, S., Vesala, M., Langguth, B., & Schlee, W. (2019). Toward Personalized Tinnitus Treatment: An Exploratory Study Based on Internet Crowdsensing. Frontiers in Public Health, 7, 157. https://doi.org/10.3389/fpubh.2019.00157
Spencer, S., Sereda, M., Schoisswohl, S., Olszewski, J., Mielczarek, M. (2019). COMPARISON OF INVASIVE VERSUS NON-INVASIVE ELECTRICAL EAR STIMULATION IN TINNITUS SUPPRESSION: LITERATURE REVIEW. Journal of Hearing Science, 9(3), 9-23. https://doi.org/10.17430/1003431
Other publications
Report for „ENT & Audiology News“ about the 12th Tinnitus Research Initiative Conference in Taipeh, Taiwan, https://www.entandaudiologynews.com/test/events/event/12th-annual-tri- tinnitus-research-initiative-conference
Report for “TinnitusHub” about the Symposium for Cortical Networks/ Neuroplasticity/ Imaging Studies at the 12th Tinnitus Research Initiative Conference in Taipeh, Taiwan, https://www.tinnitushub.com/evolution-revolution-stagnation-exclusive-insights-from- tri2019/